The Nicotinic Acetylcholine Receptor
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The Nicotinic Acetylcholine Receptor Current Views and Future Trends (Neuroscience Intelligence Unit) by Francisco Jose Barrantes

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Published by R G Landes Co .
Written in English

Subjects:

  • Medicine,
  • Internal medicine,
  • Life Sciences - Human Anatomy & Physiology,
  • Science,
  • Science/Mathematics

Book details:

The Physical Object
FormatHardcover
Number of Pages208
ID Numbers
Open LibraryOL9629598M
ISBN 100412140012
ISBN 109780412140013
OCLC/WorldCa228382348

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This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. The aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. This area of research received great impetus from the identification of the first subunit sequences to be used as neonicotinoid insecticide target sites. Although a book . Structure and Function of Insect Nicotinic Acetylcholine Receptors Studied with Nicotinoid Insecticide Affinity Probes Motohiro Tomizawa, Bachir Latli, John E. Casida Pages Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor. I. Yamamoto, J.E. Insect pest control has continuously evolved from inorganics to botanicals, to chlo­ rinated hydrocarbons, to organophosphorus compounds and methylcarbamates, then synthetic pyrethroids and most recently synthetic nicotinoids as the major classes.

Introduction This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. The nicotinic acetylcholine receptor is a transmembrane allosteric protein that mediates transduction of chemoelectric signals throughout the nervous system by opening an intrinsic ionic channel. This rapid pore opening enables flow of Na+, K +, and, in several instances, Ca 2+ ions across the cell membrane.   The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZG is analgesic Joseph R. Holtman, 1, 2 Linda P. Dwoskin, 3 Cheryl Dowell, 4 Elzbieta P. Wala, 6 Zhenfa Zhang, 3 Peter A. Crooks, 3 and J. Michael McIntosh 4, 5Cited by: ‎This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play import.

Other articles where Nicotinic acetylcholine receptor is discussed: ion channel: Toxins and disease: several other organisms; the irreversible nicotinic acetylcholine receptor antagonist alpha-bungarotoxin, from the venom of snakes in the genus Bungarus (kraits); and plant-derived alkaloids, such as strychnine and d-tubocurarine, which inhibit the activation of ion channels . Nicotinic acetylcholine receptors stand out from a large family of related proteins as being the essential initiators of every human movement, including the act of speaking. In the brain, they may help in the shaping of the words to be spoken, but in animals, they may be removed genetically from the brain with little apparent effect, except for Author: Roger L. Papke. General. Nicotinic acetylcholine receptors (nAChRs) are a family of multi-subunit transmembrane neurotransmitter receptors that are members of the ‘Cys-loop’ superfamily [1,33].They serve diverse and often critical functions throughout the central and peripheral nervous systems, and have emerging roles in non-neuronal systems [10,38].Nicotinic receptors . Insect Nicotinic Acetylcholine Receptors - Google Books The aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. .